Archived Grant Opportunity View - GO4560

The Medical Research Future Fund (MRFF) - Genomics Health Futures Mission aims to improve the lives of Australians by accelerating research that delivers more effective testing, diagnosis and treatment; facilitates the adoption of new interventions; and consolidates Australia’s international leadership in genomics.

The objective of this grant opportunity is provide grants of financial assistance to support Australian medical research and medical innovation projects that: 

• Stream 1 (Targeted Call for Research): identify and diagnose novel - primarily monogenic or oligogenic - rare diseases and increase the genomic diagnostic rate towards 70% by 2025.
• Stream 2 (Targeted Call for Research): improve early detection and targeted treatment for the most common cancers to reduce the burden of disease. Research proposals in this stream must focus on one of the following topics:
  - Topic A: discover clinically relevant biomarkers to improve early detection of common cancers
  - Topic B: develop genomic tools and technologies to identify genetic predisposition to cancer and improve screening and targeted intervention
  - Topic C: develop genomic screening tools for predictive disease modelling and to guide therapy.
• Stream 3 (Targeted Call for Research): promote diagnostic effectiveness and efficiency through better understanding of the impact of genetic variants through functional genomics by establishing a national functional genomics approach to enhance novel gene discoveries, increase diagnostic rates and enable disease modelling to support development of targeted therapies. All three Streams are intended to support large-scale interdisciplinary research.

This grant opportunity is being administered by NHMRC on behalf of the Australian Government Department of Health.

Further information on the Medical Research Future Fund is available from the Department of Health website.

Applications will only be accepted from NHMRC approved Administering Institutions. A list of NHMRC approved Administering Institutions is available from the GrantConnect GO Documents and from the NHMRC’s Administrating Institutions list on the NHMRC website.

Applications must satisfy all the requirements set out in the Medical Research Future Fund (MRFF) – Genomics Health Futures Mission – 2020 Genomics Health Futures Mission Grant Opportunity Guidelines.

The maximum project period in each Stream is as follows:

• Stream 1 (Targeted Call for Research): four years
• Stream 2 (Targeted Call for Research): four years
• Stream 3 (Targeted Call for Research): five years.

$45,000,000.00

From $500,000.00 to $6,000,000.00

Applicants are advised to read the Grant Guidelines thoroughly and liaise with the Administering Institution that will submit the application to identify any specific requirements that the Institution might have.

Applications must be submitted electronically using NHMRC’s online granting system (Sapphire).

Minimum Data closes at 5:00 pm (ACT Local Time) on 17 February 2021.

Questions should be submitted no later than 1:00 pm (ACT Local Time) on 24 February 2021.