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Grant Award View - GA32413
A phase I clinical study of adoptive transfer of regulatory T cells...
GA ID:
GA32413
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
17-Jan-2019
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$891,929.02
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
A phase I clinical study of adoptive transfer of regulatory T cells (Tregs) and low-dose interleukin-2 (IL-2) for the treatment of chronic graft-versus-host disease (GVHD): gene-marking to inform rational combination therapy
Purpose:
Bone marrow transplantation can cure leukaemia but is often complicated by graft-versus-host disease (GVHD), which greatly reduces quality- of-life. A type of immune cell, called regulatory T cells (Tregs), may help. We will expand donor Tregs in the laboratory and infuse them into patients with chronic GVHD. We will gene-mark the cells so that we can understand what happens after infusion. We will also investigate whether interleukin-2 given at the same time can make the Tregs more effective.
GO ID:
GO Title:
NHMRC Project Grant Scheme
InternalReferenceId:
GNT1163111
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
QIMR Berghofer Medical Research Institute
Recipient ABN:
31 411 813 344
Grant Recipient Location
Suburb:
Herston
Town/City:
Herston
Postcode:
4006
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, QLD
Postcode:
Multiple
Country:
AUSTRALIA