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Grant Award View - GA350861
How do unconventional T cells die?
GA ID:
GA350861
Agency:
Australian Research Council
Approval Date:
12-Dec-2023
Publish Date:
20-Dec-2023
Category:
Humanities, Arts and Social Sciences (HASS) Research
Grant Term:
1-Jan-2024 to 31-Dec-2026
Value (AUD):
$648,898.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 23/24 Discovery
Grant Program:
Discovery Projects
Grant Activity:
How do unconventional T cells die?
Purpose:
Mammalian cells die via several different mechanisms, each of which is tightly controlled at a molecular level. The choice of death pathway depends on the trigger and cell type. This project will investigate the mechanisms controlling death of T cells, including conventional T cells, and unconventional T cells, such as mucosal-associated invariant T (MAIT) cells, in normal conditions and during inflammation. It combines methods we developed to study MAIT cells in vivo with expertise in cell death analysis. This project is expected to elucidate the complex mechanisms controlling T cell survival/death and increase our fundamental understanding of cell death mechanisms of activated T cells.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2024
Internal Reference ID:
DP24 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
PARKVILLE
Town/City:
PARKVILLE
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3052
Country:
AUSTRALIA