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Grant Award View - GA215075
Resurrecting Ancient Proteins to Unlock New Catalytic Activity
GA ID:
GA215075
Agency:
Australian Research Council
Approval Date:
25-Jan-2022
Publish Date:
25-Jan-2022
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Mar-2022 to 28-Feb-2025
Original: 25-Jan-2022 to 31-Dec-2024
Value (AUD):
$530,000.00
(GST inclusive where applicable)
Variations:
- GA215075-V1 - Variation to Grant (21-Apr-2022 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Resurrecting Ancient Proteins to Unlock New Catalytic Activity
Purpose:
This project aims to study the proteins that nature uses to make penicillin and related antibiotics, and their prehistoric ancestors. By doing so, the project expects to deepen understanding of these important processes, open up ways to make new antibiotics, and generate new knowledge about protein evolution. Intended outcomes include new biocatalysts based on the ancient ones, new antibiotic compounds active against resistant bacteria, and a richer understanding of how these proteins have evolved over the last 4 billion years. This promises significant benefits in the form of new ways to address the challenge posed by antimicrobial resistance to antibiotics, which is a serious threat to the continued effectiveness of current antibiotics.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
InternalReferenceId:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
FOREST LODGE
Town/City:
FOREST LODGE
Postcode:
2037
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2037
Country:
AUSTRALIA