To access this element change to forms mode OFF
Grant Award View - GA350833
High-throughput single-molecule directed evolution
GA ID:
GA350833
Agency:
Australian Research Council
Approval Date:
12-Dec-2023
Publish Date:
20-Dec-2023
Category:
Humanities, Arts and Social Sciences (HASS) Research
Grant Term:
1-Jan-2024 to 31-Dec-2026
Value (AUD):
$598,737.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 23/24 Discovery
Grant Program:
Discovery Projects
Grant Activity:
High-throughput single-molecule directed evolution
Purpose:
DNA polymerases are essential enzymes in many biotechnological tools, including DNA sequencing and PCR tests. However, existing DNA polymerases have limitations, resulting in inaccuracies and inefficiencies. Existing methods to improve polymerases lack sensitivity to screen for subtle, yet pivotal traits. This project aims to overcome this limitation by developing a new single-molecule directed-evolution system to evolve better polymerases. With this new technology we aim to identify DNA polymerases with improved performance that benefit biotechnological applications. Additionally, these single-molecule directed-evolution methods will benefit the wider scientific community and lay the foundation for further advances in directed evolution.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2024
Internal Reference ID:
DP24 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
University of Wollongong
Recipient ABN:
61 060 567 686
Grant Recipient Location
Suburb:
KEIRAVILLE
Town/City:
KEIRAVILLE
Postcode:
2500
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2500
Country:
AUSTRALIA